Description
Procaine Benzylpenicillin is a narrow-spectrum antibiotic with bactericidal action against Gram-positive bacteria, such as Listeria, Streptococcus, Staphylococcus (not producing penicillinase), Bacillus anthracis, Corynebacterium, Clostridium, Fusobacterium and Erysipelas, Pasteurella Resistant to tetracyclines. Some strains of Haemophilus and Brucella are sensitive.
Dihydrostreptomycin shows a bactericidal action against Pasteurella, Brucella, Haemophilus, Salmonella, Shigella and Mycobacterium.
The combination of both antibiotics gives a synergistic action against most Gram-positive and Gram-negative, and prevents a rapid development of resistance against dihydrostreptomycin. Therapeutic blood levels are maintained for up to 24 hours administration.
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